Managing extremely high triglycerides

People living with Familial Chylomicronemia Syndrome (FCS) should have their lipid levels checked at least once every 3 months or more frequently as necessary.

Testing triglyceride levels at least every 3 months, or more frequently as necessary, is key to monitoring treatment and lifestyle changes for those living with extremely high triglycerides like with FCS.

Test frequently

According to the American Association of Clinical Endocrinology and the American College of Endocrinology consensus statement.

Scheduling regular triglyceride monitoring every 3 months, or more frequently as necessary, is key to understanding your patient’s risk.

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Not an actual patient.

National Lipid Association guidelines recommend a very low-fat diet (total fat 10-15% of total calories) for patients with FCS

Diet and meal planning are also important factors for managing extremely high triglycerides. Did you know that just one meal can spike triglyceride levels and increase the associated risk of acute pancreatitis?

National Lipid Association fact sheet on FCS diet

Learn about an FDA-approved medicine to treat FCS

For some people, traditional triglyceride-lowering therapies and intensive dieting are not enough to lower levels and reduce acute pancreatitis risk.

See the impact
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Show References Expand Collapse

  1. Handelsman Y, Jellinger PS, Guerin CK, et al. Consensus statement by the American Association of Clinical Endocrinologists and American College of Endocrinology on the management of dyslipidemia and prevention of cardiovascular disease algorithm – 2020 executive summary. Endocr Pract. 2020;26(10):1196-1224.
  2. Grundy SM, Stone NJ, Bailey AL, et al. 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA guideline on the management of blood cholesterol: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Circulation. 2019;139(25):e1046-e1081.
  3. Javed F, Hegele R, Garg A, et al. Familial chylomicronemia syndrome: an expert clinical review from the National Lipid Association. J Clin Lipidol. 2025;19(3):382-403.
  4. Goldberg RB, Chait A. A comprehensive update on the chylomicronemia syndrome. Front Endocrinol (Lausanne). 2020;11:593931.

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