For people with extremely high triglycerides despite standard of care
Expert guidelines support lowering triglycerides below 500 mg/dL to reduce the risk of acute pancreatitis
Aim Lower
Imagine achieving the expert guideline-recommended goal for triglycerides
People with extremely high triglycerides, >880 mg/dL, who do not respond to traditional triglyceride-lowering therapies need treatment to lower their risk of acute pancreatitis. Strict diets can lower triglyceride levels but are hard to maintain, while traditional triglyceride-lowering therapies do not lower triglycerides enough to adequately reduce acute pancreatitis risk.
Reducing the risk of acute pancreatitis
Imagine if we could get people to lower their triglycerides below 500 mg/dL to reduce the risk of acute pancreatitis.
See the risk
Expert guidelines support lowering triglycerides below 500 mg/dL to reduce the risk of acute pancreatitis.
What to look for when diagnosing patients
Extremely high triglycerides can be a sign of Familial Chylomicronemia Syndrome (FCS), which can be clinically diagnosed or genetically confirmed. This checklist may help you identify patients with FCS. Consider a diagnosis of FCS in people who consistently have extremely high triglycerides despite treatment. Diagnosis can be confirmed with at least one of the following:
Prior history of acute
pancreatitis
Hospitalizations for severe abdominal pain without other explainable cause
Family history of hypertriglyceridaemia-induced acute pancreatitis
History of childhood
pancreatitis
Genetic testing
(if possible)
There are few options to keep triglycerides in check
For some people, the use of traditional triglyceride-lowering therapies and intensive dieting are not enough to lower levels and reduce acute pancreatitis risk.
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Show References
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